Description

Iodipine CAS NO 98647-67-7 is a high-purity chemical compound belonging to the dihydropyridine class, primarily utilized as a key intermediate in advanced pharmaceutical synthesis. Its structural significance lies in enabling the development of calcium channel blockers and other active pharmaceutical ingredients (APIs) targeting cardiovascular and neurological conditions. This product is essential for research institutions, pharmaceutical R&D laboratories, and fine chemical manufacturers engaged in the development of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of calcium channel blocker drugs and other dihydropyridine-based active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry research for developing new drug candidates targeting cardiovascular and neurological pathways.
• Fine Chemical Synthesis: Serves as a versatile intermediate in multi-step organic syntheses for complex molecules in the pharmaceutical and agrochemical sectors.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and impurity profiling.

Basic Information

Product Name	Iodipine
CAS No.	98647-67-7
Molecular Formula	C19H18IN2O6
Molecular Weight	512.26 g/mol
Synonyms	Iodipine; 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester; Isopropyl methyl 4-(2,1,3-benzoxadiazol-4-yl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate; 4-(2,1,3-Benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl isopropyl ester; BIBR 1048 (historical code)
EINECS	Contact for details

Quality Control

Our Iodipine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, to meet the stringent requirements for pharmaceutical intermediates. A Certificate of Analysis (COA) detailing all test results is provided with every shipment, and we support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from heat, open flames, and incompatible materials. Due to its light-sensitive nature, handling and packaging should be conducted under amber light or in light-protected conditions.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.