Description

Benazepril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used primarily as an active pharmaceutical ingredient (API). Its primary value lies in its efficacy for managing hypertension and heart failure by inhibiting the conversion of angiotensin I to the vasoconstrictor angiotensin II. This compound is essential for pharmaceutical manufacturers developing cardiovascular medications, including combination therapies. Benazepril CAS NO 98626-50-7 is a critical component in the global supply chain for life-saving drugs.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription antihypertensive and heart failure medications.
• Tablet Formulation: Used in the manufacturing of oral solid dosage forms, often in combination with other APIs like hydrochlorothiazide or amlodipine.
• Cardiovascular Research: Serves as a key reference standard and research chemical in preclinical and clinical studies of ACE inhibition.
• Generic Drug Production: A fundamental component for manufacturers producing generic versions of branded ACE inhibitor drugs.
• Veterinary Medicine: Applied in certain veterinary formulations for managing hypertension in companion animals.
• Bulk Pharmaceutical Intermediates: May be used in the synthesis of more complex pharmaceutical molecules or prodrugs.

Basic Information

Product Name	Benazepril
CAS No.	98626-50-7
Molecular Formula	C24H28N2O5•HCl
Molecular Weight	460.95 g/mol (as hydrochloride)
Synonyms	Benazepril Hydrochloride; CGS-14824A; CGS 14824; (3S)-3-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride; Benzazepril; Lotensin (Brand Name); Briem; Zinadril; Cibacen
EINECS	Contact for details

Quality Control

Our Benazepril is manufactured under strict quality management systems, targeting compliance with major pharmacopoeial standards such as USP and EP. Every batch undergoes comprehensive analytical testing, including identification, assay, impurity profiling, and residual solvent analysis. A Certificate of Analysis (COA) detailing all test results against release specifications is provided with each shipment to ensure full traceability and regulatory compliance for our pharmaceutical partners.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.