Description

K-13 (Ace Inhib) is a high-purity pharmaceutical intermediate and research chemical, specifically designed for the synthesis of advanced active pharmaceutical ingredients (APIs). This compound is of critical importance in the development and manufacturing of cardiovascular medications, particularly those targeting the renin-angiotensin system. It is an essential building block for researchers and manufacturers in the pharmaceutical and biotechnology sectors who require reliable, high-quality raw materials for drug discovery and production. The product is supplied under strict quality control to ensure batch-to-batch consistency for demanding applications.

Application

• Pharmaceutical Intermediate: Primary use as a key synthetic precursor in the manufacture of Angiotensin-Converting Enzyme (ACE) inhibitor APIs.
• Drug Discovery & Research: Serves as a critical scaffold or building block in medicinal chemistry for developing new cardiovascular therapeutics.
• Process Development: Used in the optimization and scale-up of synthetic routes for commercial pharmaceutical production.
• Reference Standard: Can be utilized as an analytical standard for quality control and method validation in API manufacturing.
• Biochemical Research: Employed in enzymatic studies and biochemical assays related to ACE activity and inhibition mechanisms.

Basic Information

Product Name	K-13 (Ace Inhib)
CAS No.	108890-90-0
Molecular Formula	C21H28N2O5
Molecular Weight	388.46 g/mol
Synonyms	(2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]octahydro-1H-indole-2-carboxylic acid; Perindopril Intermediate; Perindoprilat Ethyl Ester; S 9780; Ace Inhibitor Intermediate K-13; 1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino]propanoyl]-octahydroindole-2-carboxylic acid; S-9780.
EINECS	Contact for details

Quality Control

Our K-13 (Ace Inhib) is manufactured under a quality management system and undergoes rigorous analytical testing to ensure it meets the stringent requirements for pharmaceutical intermediates. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We can support compliance with relevant pharmacopeial standards (e.g., USP, EP) upon request, ensuring reliable integration into your regulated manufacturing processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere if necessary to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.