Description

Cilazapril CAS NO 106860-20-2 is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor belonging to the class of prodrugs. It is a critical active pharmaceutical ingredient (API) valued for its role in cardiovascular therapy. This compound is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of antihypertensive and heart failure medications.

Application

• Primary Pharmaceutical Ingredient: Core active component in the formulation of prescription medications for the treatment of hypertension (high blood pressure).
• Cardiac Therapy: Used in drugs for managing congestive heart failure, improving hemodynamics and patient outcomes.
• Pharmaceutical R&D: Serves as a key reference standard and intermediate in preclinical and clinical research for new cardiovascular drugs.
• Generic Drug Manufacturing: Essential for producing cost-effective generic versions of cilazapril-based medications for global markets.
• Biochemical Research: Utilized in pharmacological studies to investigate ACE inhibition mechanisms and related biochemical pathways.

Basic Information

Product Name	Cilazapril
CAS No.	106860-20-2
Molecular Formula	C22H31N3O5
Molecular Weight	417.50 g/mol
Synonyms	Cilazapril; Cilazaprilum; Ro 31-2848; (1S,9S)-9-[[(1S)-1-Carboxy-3-phenylpropyl]amino]octahydro-10-oxo-6H-pyridazino[1,2-a][1,2]diazepine-1-carboxylic acid; Inhibace; Vascace; Dynorm
EINECS	Contact for details

Quality Control

Our Cilazapril is manufactured under strict quality management systems, targeting high purity suitable for pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including HPLC for assay and related substances, to ensure it meets stringent in-house specifications. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.