Description

Stenopril CAS NO 13005-65-7 is a high-purity pharmaceutical intermediate and fine chemical compound. It is a critical building block in the synthesis of active pharmaceutical ingredients (APIs), particularly in the cardiovascular and antihypertensive therapeutic classes. This compound is essential for manufacturers in the pharmaceutical, biotechnology, and advanced chemical synthesis sectors requiring reliable, high-quality raw materials for complex production processes.

Application

• Pharmaceutical Intermediate: Primary use as a key synthon in the production of angiotensin-converting enzyme (ACE) inhibitors and related cardiovascular drugs.
• Active Pharmaceutical Ingredient (API) Synthesis: Serves as a crucial precursor in multi-step synthetic routes for final API manufacturing.
• Biochemical Research: Used in R&D laboratories for studying enzyme inhibition mechanisms and developing new therapeutic candidates.
• Fine Chemical Production: Employed in the custom synthesis of complex, high-value organic molecules for specialized applications.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP-compliant drug substance production.

Basic Information

Product Name	Stenopril
CAS No.	13005-65-7
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Stenopril; (S)-1-[(S)-2-Methyl-3-sulfanylpropanoyl]pyrrolidine-2-carboxylic acid; L-Proline, 1-[(2S)-3-mercapto-2-methyl-1-oxopropyl]-; SQ 14,225 (Captopril related); ACE Inhibitor Intermediate; 13005-65-7; 1-[(2S)-3-Mercapto-2-methylpropionyl]-L-proline
EINECS	Contact for details

Quality Control

Our Stenopril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and impurity profiles, suitable for pharmaceutical applications. Certificates of Analysis (COA) documenting results for assay, related substances, residual solvents, and other critical parameters are provided with every shipment. We support compliance with cGMP, ICH Q7, and other relevant pharmaceutical guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated area at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and light-sensitive; containers must be kept tightly sealed to exclude moisture and stored away from direct light exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Optical Rotation	Specific range provided on COA

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.