Description

Perindopril Erbumine is the tert-butylamine salt of the angiotensin-converting enzyme (ACE) inhibitor, perindopril. This high-purity active pharmaceutical ingredient (API) is critical for the formulation of cardiovascular medications that effectively manage hypertension and heart failure. It is primarily required by pharmaceutical manufacturers and research institutions engaged in the development and production of prescription drugs. Our supply ensures consistent quality and reliable availability for global pharmaceutical applications.

Application

• Pharmaceutical API: Primary active ingredient in antihypertensive and heart failure medications.
• Finished Dosage Formulation: Used in the manufacture of tablets, capsules, and other solid oral dosage forms.
• Cardiovascular Research: Serves as a key reference standard and investigational compound in pharmacological studies.
• Generic Drug Manufacturing: Essential for producing bioequivalent generic versions of branded ACE inhibitor drugs.
• Clinical Trial Material: Supplied as GMP-grade material for use in Phase I-III clinical studies.
• Analytical Reference Standard: Used in quality control laboratories for HPLC/UV assay development and validation.

Basic Information

Product Name	Perindopril Erbumine
CAS No.	107133-36-8
Molecular Formula	C19H32N2O5•C4H11N
Molecular Weight	441.60 g/mol (as free base: 368.47)
Synonyms	Perindopril tert-Butylamine Salt; S-9780; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid tert-butylamine salt; Coversyl (brand name); Aceon (brand name); Perindoprilum; Perindopril Erbumin
EINECS	Contact for details

Quality Control

Our Perindopril Erbumine is manufactured under strict quality systems and is typically supplied to meet Pharmaceutical Grade standards, including potential compliance with USP, EP, and ICH guidelines. Each batch undergoes rigorous analytical testing for identity, purity, and impurities. Certificates of Analysis (COA) documenting full specifications are available upon request to support your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.