Description

Libenzapril CAS NO 109214-55-3 is a high-purity active pharmaceutical ingredient (API) belonging to the angiotensin-converting enzyme (ACE) inhibitor class. This compound is critical for the research and development of novel cardiovascular therapeutics, offering a pathway to advanced treatment formulations. It is primarily utilized by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic research institutions focused on hypertension and heart failure drug discovery.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of cardiovascular medications.
• Reference Standard: Used for analytical method development, validation, and quality control testing in pharmaceutical laboratories.
• Biochemical Research: Serves as a key reagent in studies investigating the renin-angiotensin system and ACE inhibition mechanisms.
• Preclinical Development: Essential for pharmacokinetic, pharmacodynamic, and toxicology studies during drug candidate screening.
• Process Chemistry: Intermediate or starting material for the synthesis of related ACE inhibitor analogs and derivatives.

Basic Information

Product Name	Libenzapril
CAS No.	109214-55-3
Molecular Formula	C21H28N2O5
Molecular Weight	388.46 g/mol
Synonyms	Libenzapril; (S)-1-[6-Amino-2-[[hydroxy(4-phenylbutyl)phosphinyl]oxy]-1-oxohexyl]-L-proline; CGS 30440; CGS-30440; Libenzaprilum; UNII-6I3K30563S
EINECS	Contact for details

Quality Control

Our Libenzapril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical research. Specifications typically align with pharmacopeial guidelines for APIs. A detailed Certificate of Analysis (COA), including results for identity, purity, and related substances, is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.