Description

Fosinopril CAS NO 97825-24-6 is an angiotensin-converting enzyme (ACE) inhibitor belonging to the phosphonate chemical class. This compound is a critical active pharmaceutical ingredient (API) valued for its role in cardiovascular therapy. It is primarily required by pharmaceutical manufacturers and research institutions for the formulation of antihypertensive and heart failure medications.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for the treatment of hypertension (high blood pressure).
• Cardiovascular Drug Formulation: Used in the development and production of tablets and other dosage forms for managing congestive heart failure.
• Pharmacological Research: Serves as a key reference standard and intermediate in cardiovascular disease research and drug discovery programs.
• Generic Drug Manufacturing: Essential for companies producing bioequivalent generic versions of branded fosinopril medications.
• Metabolite Studies: Used in analytical laboratories for the study of its active metabolite, fosinoprilat, and related pharmacokinetics.

Basic Information

Product Name	Fosinopril
CAS No.	97825-24-6
Molecular Formula	C30H46NO7P
Molecular Weight	563.66 g/mol
Synonyms	Fosinopril Sodium; SQ 28,555; SQ-28555; (2S,4S)-4-Cyclohexyl-1-[2-[[(1S)-1-carboxy-3-phenylpropyl]amino]-1-oxopropyl]-2-methyl-2,5-dihydro-1H-pyrrole-2-carboxylic acid 1-ethyl ester 4-oxide; Phosphinicin; Monopril (brand name); Staril (brand name); Dynacil (brand name)
EINECS	Contact for details

Quality Control

Our Fosinopril is manufactured under strict quality management systems. We provide material that meets high-purity standards suitable for pharmaceutical applications, with testing aligned with major pharmacopoeial guidelines. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each batch to ensure traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.