Description

Clentiazem Maleate CAS NO 96128-92-6 is a high-purity pharmaceutical intermediate and research chemical, specifically a calcium channel blocker derivative. It is a critical building block in the synthesis of advanced cardiovascular active pharmaceutical ingredients (APIs) and serves as a key reference standard in analytical research. This compound is essential for pharmaceutical R&D laboratories, API manufacturers, and academic institutions focused on cardiovascular pharmacology and drug development.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of advanced calcium channel blocker drugs and related cardiovascular therapeutics.
• Active Pharmaceutical Ingredient (API) Development: Serves as a key precursor or building block in the research and production of novel APIs targeting hypertension and angina.
• Reference Standard: Used as a certified reference material (CRM) in analytical laboratories for method development, validation, and quality control testing of related pharmaceutical products.
• Biochemical Research: Employed in pharmacological studies to investigate calcium channel mechanisms, vascular smooth muscle function, and cardiac electrophysiology.
• Process Chemistry: Utilized in scaling up synthetic routes and optimizing manufacturing processes for diltiazem-related compounds.

Basic Information

Product Name	Clentiazem Maleate
CAS No.	96128-92-6
Molecular Formula	C26H33N2O6S • C4H4O4
Molecular Weight	604.66 g/mol
Synonyms	Clentiazem Maleate; TA-3090 Maleate; (2S,3S)-5-[2-(Dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-3-(2,2,2-trifluoroethoxy)-4(1H)-benzothiazepin-4-one maleate; 1,5-Benzothiazepin-4(5H)-one, 5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-3-(2,2,2-trifluoroethoxy)-, (2S,3S)-, (2Z)-2-butenedioate (1:1); TA3090 Maleate
EINECS	Contact for details

Quality Control

Our Clentiazem Maleate is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and residual solvent determination, to ensure it meets stringent specifications for pharmaceutical use. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming identity, purity, and conformance to agreed specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and light-sensitive; therefore, containers must be kept tightly sealed in a dry environment and away from direct light exposure to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Chiral Purity	≥99.0%
Related Substances (HPLC)	Total impurities ≤1.5%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.