Description

Clentiazem is a high-purity pharmaceutical intermediate and research chemical of significant interest in medicinal chemistry. Its primary value lies in its role as a key synthetic precursor for the development of novel calcium channel blockers and other cardiovascular agents. This compound is essential for researchers and manufacturers in the pharmaceutical and biotechnology sectors engaged in drug discovery, process development, and analytical method validation.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of advanced calcium channel modulators and related therapeutic compounds.
• Research & Development: Used in academic and industrial laboratories for pharmacological studies, structure-activity relationship (SAR) analysis, and metabolic pathway investigation.
• Reference Standard: Serves as a high-purity analytical standard for quality control (QC) and regulatory compliance testing in API manufacturing.
• Process Chemistry: Employed in scaling up synthetic routes and optimizing production processes for cardiovascular drugs.

Basic Information

Product Name	Clentiazem
CAS No.	96125-53-0
Molecular Formula	C22H27N3O4S
Molecular Weight	429.54 g/mol
Synonyms	Clentiazem; TA-3090; (±)-Clentiazem; 8-Chloro-2,3-dihydro-2-(4-methoxyphenyl)-1,3-dimethyl-1H-1,5-benzodiazepine-4(5H)-thione; 8-Chloro-2-(4-methoxyphenyl)-1,3-dimethyl-1,3,4,5-tetrahydro-2H-1,5-benzodiazepine-4-thione
EINECS	Contact for details

Quality Control

Our Clentiazem is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. A Certificate of Analysis (COA) detailing all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.