Description

Sornidipine is a potent and selective dihydropyridine calcium channel blocker. This high-purity active pharmaceutical ingredient (API) is critical for the research and development of next-generation cardiovascular therapeutics. It is primarily utilized by pharmaceutical manufacturers and advanced research institutions focused on hypertension and related vascular disorders. Our supply ensures the stringent quality and consistency required for demanding pharmaceutical applications.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihypertensive drug formulations.
• Cardiovascular Research: A key reference standard and tool compound for studying calcium channel mechanisms in vascular smooth muscle.
• Preclinical Development: Used in pharmacological studies and toxicology assessments for new drug candidates.
• Analytical Standard: Serves as a high-purity standard for method development and quality control (HPLC, GC, MS) in analytical laboratories.
• Process Chemistry: Employed in the synthesis and scale-up optimization of related dihydropyridine derivatives.

Basic Information

Product Name	Sornidipine
CAS No.	95105-77-4
Molecular Formula	C₂₇H₃₄N₂O₇
Molecular Weight	498.57 g/mol
Synonyms	CS-905; Sornidipine; (E)-3-[2-[Phenyl(pyridin-2-yl)methylideneamino]oxyethyl] 5-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 2,6-Dimethyl-3,5-dicarbomethoxy-4-(3-nitrophenyl)-1,4-dihydropyridine 2-[N-(α-pyridyl)benzylideneamino]oxyethyl ester; 4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[2-[(E)-(phenyl)(2-pyridinyl)methylene]amino]oxyethyl] ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Sornidipine is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identification by IR and NMR, to ensure it meets exacting pharmaceutical-grade standards. A detailed Certificate of Analysis (COA) is provided with each shipment to guarantee traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.5% Any single impurity ≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.