Description

Cilazapril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used as an active pharmaceutical ingredient (API). It is a critical compound for the development and manufacturing of cardiovascular medications, primarily used to treat hypertension and heart failure. This high-purity intermediate is essential for pharmaceutical manufacturers and research institutions focused on cardiovascular therapeutics and drug discovery.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihypertensive and heart failure medications.
• Drug Formulation: Used in the development and production of solid oral dosage forms such as tablets and capsules.
• Research & Development: Serves as a key reference standard and intermediate in cardiovascular drug discovery programs.
• Clinical Trial Material: Manufactured under controlled conditions for use in clinical studies.
• Generic Drug Manufacturing: A vital component for companies producing generic versions of ACE inhibitor drugs.

Basic Information

Product Name	Cilazapril
CAS No.	92077-78-6
Molecular Formula	C22H31N3O5
Molecular Weight	417.50 g/mol
Synonyms	(S)-1-[(S)-6-Oxo-2-(1H-pyrazol-1-yl)-1,6-dihydropyrimidin-1-yl]-4-phenylbutan-2-yl (2S,3aR,7aS)-1-[(2S)-2-{[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino}propanoyl]octahydro-1H-indole-2-carboxylate; Ro 31-2848; Inhibace; Vascace; Cilazaprilum; Cilazaprilo
EINECS	Contact for details

Quality Control

Our Cilazapril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided and can be tailored to meet specific pharmacopeial requirements (e.g., USP, EP).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect this moisture-sensitive material.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.