Description

Benidipine Hydrochloride is a high-purity pharmaceutical active ingredient belonging to the dihydropyridine class of calcium channel blockers. This compound is critical for the research and development of antihypertensive and antianginal medications, offering precise control over cardiovascular activity. It is primarily utilized by pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in cardiovascular drug discovery and formulation.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of prescription antihypertensive drugs.
• Reference Standard: Used in analytical laboratories for quality control, method development, and validation of benidipine-based products.
• Biochemical Research: Tool compound for studying L-type and T-type calcium channels in cardiovascular and neurological research.
• Preclinical Studies: Investigational material for pharmacokinetics, pharmacodynamics, and toxicology assessments.
• Generic Drug Development: Serves as the key starting material for companies developing generic versions of benidipine medications.

Basic Information

Product Name	Benidipine Hydrochloride
CAS No.	91599-76-7
Molecular Formula	C28H31N3O6·HCl
Molecular Weight	542.02 g/mol
Synonyms	Benidipine HCl; (±)-Benidipine Hydrochloride; Coniel (trade name); KW-3049; 3-[(3R)-1-Benzyl-3-piperidinyl] methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate hydrochloride; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-[1-(phenylmethyl)-3-piperidinyl] ester hydrochloride
EINECS	Contact for details

Quality Control

Our Benidipine Hydrochloride is manufactured under strict quality management systems. Each batch is tested to ensure it meets high-purity standards suitable for pharmaceutical research and development. A comprehensive Certificate of Analysis (COA) is provided, detailing results for identity, purity, and impurity profiles via validated methods such as HPLC, NMR, and IR spectroscopy.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.