Description

Benidipine is a potent and highly selective dihydropyridine-class calcium channel blocker (CCB) primarily used in pharmaceutical research and development. Its core value lies in its long-lasting action and vascular selectivity, making it a key compound for studying cardiovascular therapeutics. This product is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing treatments for hypertension and angina.

Application

• Pharmaceutical Active Ingredient (API): Serves as the primary active component in the formulation of antihypertensive and antianginal medications.
• Reference Standard: Used as a high-purity analytical standard in quality control (QC) and quality assurance (QA) laboratories for method development and validation.
• Biochemical Research: Employed in pharmacological studies to investigate calcium channel mechanisms, vascular smooth muscle function, and cardiovascular disease models.
• Preclinical Development: A critical intermediate in the research and development pipeline for new cardiovascular drugs.
• Formulation Studies: Used in the development of various drug delivery systems, including tablets and controlled-release formulations.

Basic Information

Product Name	Benidipine
CAS No.	91599-75-6
Molecular Formula	C28H31N3O6
Molecular Weight	505.56 g/mol
Synonyms	(±)-Benidipine; FRC-8653; KW-3049; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(1-benzyl-3-piperidinyl) ester 5-methyl ester; Coniel; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[1-(phenylmethyl)-3-piperidinyl] ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Benidipine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. The product is suitable for pharmaceutical research and development applications. Comprehensive testing is performed, including identity confirmation, purity assay, and impurity profiling. A Certificate of Analysis (COA) detailing all specifications and test results is provided with each batch to support your regulatory and quality requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). Keep the container tightly sealed to protect from moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.