Description

Methyl 1,4-Dihydro-2,6-Dimethyl-4-(2Trifluoromethyl)Phenyl-Pyridine-3-Carboxylate-5-(3,4-Dimethoxyphenyl)Ethyl Carboxamide is a high-purity, advanced pharmaceutical intermediate with a complex heterocyclic structure. This compound matters for its critical role in the synthesis of active pharmaceutical ingredients (APIs), particularly in cardiovascular and neurological research. It is primarily needed by pharmaceutical R&D laboratories, fine chemical manufacturers, and contract research organizations (CROs) engaged in developing novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel dihydropyridine-class calcium channel blockers and other therapeutic molecules.
• Research & Development: Used in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Fine Chemical Synthesis: Serves as a precursor for creating more complex, functionalized chemical entities in multi-step organic syntheses.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for cGMP production of clinical trial materials.
• Academic Research: Utilized in university and institutional labs for studying heterocyclic chemistry and pharmacological mechanisms.
• Reference Standard: Can be supplied as a high-purity analytical standard for quality control and method development in analytical laboratories.

Basic Information

Product Name	Methyl 1,4-Dihydro-2,6-Dimethyl-4-(2Trifluoromethyl)Phenyl-Pyridine-3-Carboxylate-5-(3,4-Dimethoxyphenyl)Ethyl Carboxamide
CAS No.	887406-97-5
Molecular Formula	C27H27F3N2O5
Molecular Weight	516.51 g/mol
Synonyms	5-[(3,4-Dimethoxyphenethyl)carbamoyl]-2,6-dimethyl-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine-3-carboxylic acid methyl ester; Methyl 5-[(2-(3,4-dimethoxyphenyl)ethyl)carbamoyl]-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-1,4-dihydropyridine-3-carboxylate; CAS 887406-97-5; 1,4-Dihydropyridine-3,5-dicarboxamide derivative; DHP derivative with trifluoromethyl and dimethoxyphenethyl groups; Advanced DHP intermediate; Trifluoromethylphenyl dihydropyridine carboxamide.
EINECS	Contact for details

Quality Control

Our Methyl 1,4-Dihydro-2,6-Dimethyl-4-(2Trifluoromethyl)Phenyl-Pyridine-3-Carboxylate-5-(3,4-Dimethoxyphenyl)Ethyl Carboxamide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.