Description

Imidapril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used as an active pharmaceutical ingredient (API). It is a critical compound for the development and manufacture of antihypertensive and cardiovascular medications. This high-purity intermediate is essential for pharmaceutical manufacturers and research institutions focused on cardiology and metabolic syndrome treatments.

Application

• Primary Pharmaceutical Ingredient: Core API in the formulation of prescription medications for the treatment of hypertension (high blood pressure).
• Cardiovascular Drug Synthesis: Used in the production of drugs for heart failure and for the prevention of diabetic nephropathy.
• Pharmaceutical Research & Development: Serves as a key reference standard and building block in preclinical and clinical research for new cardiovascular therapies.
• Generic Drug Manufacturing: A vital component for companies producing bioequivalent generic versions of branded ACE inhibitor drugs.
• Active Metabolite: Acts as a prodrug, metabolizing into the active diacid form, Imidaprilat, within the body.

Basic Information

Product Name	Imidapril
CAS No.	89371-37-9
Molecular Formula	C20H27N3O6
Molecular Weight	405.45 g/mol
Synonyms	Imidapril Hydrochloride; (4S)-3-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-1-methyl-2-oxo-4-imidazolidinecarboxylic acid hydrochloride; TA-6366; Cilazapril analog; ACE Inhibitor TA-6366
EINECS	Contact for details

Quality Control

Our Imidapril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for pharmaceutical use, including identity, purity, and impurity profiles. Certificates of Analysis (COA) documenting compliance with relevant pharmacopeial standards (such as USP/EP) are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.0% - 102.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Maximum Impurity	≤ 0.5%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.