Description

Amlodipine is a high-purity active pharmaceutical ingredient (API) belonging to the dihydropyridine class of calcium channel blockers. It is a critical component in the formulation of antihypertensive and antianginal medications, valued for its long-acting efficacy and favorable safety profile. This compound is essential for pharmaceutical manufacturers and research institutions developing treatments for cardiovascular diseases. The product is supplied as Amlodipine CAS NO 88150-42-9, meeting stringent quality standards for global pharmaceutical applications.

Application

• Pharmaceutical API: Primary active ingredient in the manufacture of tablets and other dosage forms for hypertension and angina.
• Cardiovascular Drug Formulation: Used in the development and production of long-acting calcium channel blocker medications.
• Reference Standard: Serves as a certified reference material (CRM) for quality control and analytical method development in laboratories.
• Research & Development: Key intermediate in pharmacological studies and the synthesis of novel therapeutic analogs.
• Generic Drug Manufacturing: Critical for producing cost-effective generic versions of branded amlodipine medications.
• Combination Therapies: Used in fixed-dose combination drugs alongside other antihypertensive agents like benazepril or atorvastatin.

Basic Information

Product Name	Amlodipine
CAS No.	88150-42-9
Molecular Formula	C20H25ClN2O5
Molecular Weight	408.88 g/mol
Synonyms	Amlodipine Besylate (salt form); Amlodipine Maleate; 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydropyridine-3,5-dicarboxylate; Norvasc (Brand Name); Amlodip; Amlong; Amcard; Istin; Amlodipino; Amlodipinum
EINECS	Contact for details

Quality Control

Our Amlodipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for assay and impurity profiling, to ensure compliance with major pharmacopoeial standards such as USP, EP, and CP. A Certificate of Analysis (COA) detailing purity, related substances, residual solvents, and other critical parameters is provided with every shipment to guarantee traceability and product integrity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The product is light-sensitive (store away from light) and should be handled accordingly to maintain stability and potency.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms
Identification (HPLC)	Conforms
Assay (HPLC)	98.5% - 101.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 0.5% Any individual impurity ≤ 0.1%
Water (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.