Description

Dehydronitrosonisoldipine is a specialized chemical intermediate primarily used in advanced pharmaceutical research and development. This compound is critical for the synthesis and study of novel calcium channel blockers and related cardiovascular agents. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on developing new therapeutic entities and conducting metabolic pathway studies.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of next-generation dihydropyridine calcium channel blockers and their derivatives.
• Metabolite Reference Standard: Used as an analytical standard in pharmacokinetic and drug metabolism studies for related pharmaceutical compounds.
• Medicinal Chemistry Research: Serves as a precursor or model compound for structure-activity relationship (SAR) studies in cardiovascular drug discovery.
• Process Development: Employed in the development and optimization of synthetic routes for complex active pharmaceutical ingredients (APIs).
• Analytical Testing: Utilized as a high-purity reference material in quality control laboratories for method development and validation.

Basic Information

Product Name	Dehydronitrosonisoldipine
CAS No.	87375-91-5
Molecular Formula	C20H19N3O6
Molecular Weight	397.38 g/mol
Synonyms	Dehydronitrosonisoldipine; 2,6-Dimethyl-4-(2-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid 3-(2-methoxyethyl) 5-methyl ester N-oxide; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)-, 3-(2-methoxyethyl) 5-methyl ester, 1-oxide; Nisoldipine Impurity; Nisoldipine Related Compound; Bay k 5552 Impurity
EINECS	Contact for details

Quality Control

Our Dehydronitrosonisoldipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to orange crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.