Description

2,6-Dimethyl-3,5-Dicarbomethoxy-4-(o-Difluoromethylthiophenyl)-1,4-Dihydropyridine is a high-purity, specialized dihydropyridine derivative of significant interest in advanced pharmaceutical research and development. This compound serves as a critical synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor for novel therapeutic agents. It is primarily utilized by research institutions and pharmaceutical companies engaged in the development of calcium channel blockers and other cardiovascular or neurological drugs. The precise molecular architecture offers a valuable scaffold for medicinal chemistry, enabling the exploration of new structure-activity relationships.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel 1,4-dihydropyridine-based calcium channel antagonists.
• Medicinal Chemistry Research: Valuable scaffold for drug discovery programs targeting cardiovascular diseases, hypertension, and neurological disorders.
• Chemical Reference Standard: Used as a high-purity standard for analytical method development, validation, and quality control in API manufacturing.
• Process Chemistry Development: Serves as an intermediate in optimizing scalable synthetic routes for potential active pharmaceutical ingredients (APIs).
• Biochemical Research: Potential tool compound for studying ion channel function and related biochemical pathways in vitro.

Basic Information

Product Name	2,6-Dimethyl-3,5-Dicarbomethoxy-4-(o-Difluoromethylthiophenyl)-1,4-Dihydropyridine
CAS No.	87240-31-1
Molecular Formula	C19H19F2NO4S
Molecular Weight	395.42 g/mol
Synonyms	4-(2-(Difluoromethylthio)phenyl)-2,6-dimethyl-3,5-dicarbomethoxy-1,4-dihydropyridine; 3,5-Dimethyl 2,6-dimethyl-4-[2-[(difluoromethyl)sulfanyl]phenyl]-1,4-dihydro-3,5-pyridinedicarboxylate; 1,4-DHP derivative with o-difluoromethylthiophenyl substitution; CAS 87240-31-1; Difluoromethylthiophenyl DHP derivative
EINECS	Contact for details

Quality Control

Our 2,6-Dimethyl-3,5-Dicarbomethoxy-4-(o-Difluoromethylthiophenyl)-1,4-Dihydropyridine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the stringent requirements for research and development use. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and compliance with your specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat and incompatible materials. The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.