Description

Aranidipine is a potent and selective dihydropyridine-class calcium channel blocker. This compound is primarily utilized as a key pharmaceutical intermediate in the research and development of antihypertensive and antianginal medications. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions focused on cardiovascular drug discovery and production. Our supply ensures high purity and batch-to-batch consistency critical for advanced pharmaceutical synthesis.

Application

• Pharmaceutical Intermediate: Primary use as a critical building block in the synthesis of advanced calcium channel antagonist drugs.
• Active Pharmaceutical Ingredient (API) Research: Serves as a reference standard and starting material in the development of new cardiovascular APIs.
• Biochemical Research: Used in pharmacological studies to investigate calcium channel mechanisms and vascular smooth muscle function.
• Analytical Standard: Employed as a high-purity standard in HPLC, LC-MS, and other analytical methods for quality control and method validation.
• Preclinical Studies: Utilized in animal model research for evaluating the efficacy and pharmacokinetics of dihydropyridine derivatives.

Basic Information

Product Name	Aranidipine
CAS No.	86780-90-7
Molecular Formula	C19H21N3O6
Molecular Weight	387.39 g/mol
Synonyms	Aranidipine; (±)-Aranidipine; CS-905; 3-O-(4-(N-Benzyl-N-methylamino)butyl) 5-O-methyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid 3-[4-(N-benzyl-N-methylamino)butyl] ester 5-methyl ester
EINECS	Contact for details

Quality Control

Our Aranidipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, residual solvent analysis, and identity confirmation (IR, NMR) to ensure it meets stringent specifications for pharmaceutical intermediate use. Certificates of Analysis (COA) are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light yellow crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.