Description

Felodipine is a high-purity, selective calcium channel blocker belonging to the dihydropyridine class. This active pharmaceutical ingredient (API) is critical for the formulation of antihypertensive medications, offering precise vasodilation to manage blood pressure. It is essential for pharmaceutical manufacturers and research institutions developing cardiovascular therapies. Our product, Felodipine CAS NO 86189-69-7, is supplied under stringent quality control to ensure reliability for your production and R&D needs.

Application

• Pharmaceutical API: Primary use as the active ingredient in antihypertensive and antianginal drug formulations.
• Finished Dosage Forms: Manufacture of extended-release tablets and other oral solid dosage forms for controlled drug delivery.
• Research & Development: A key reference standard and intermediate in pharmacological studies and new drug development projects.
• Generic Drug Production: Sourcing for the cost-effective production of generic versions of branded calcium channel blockers.
• Clinical Trial Materials: Supply of GMP-grade material for use in clinical studies and bioavailability testing.

Basic Information

Product Name	Felodipine
CAS No.	86189-69-7
Molecular Formula	C18H19Cl2NO4
Molecular Weight	384.25 g/mol
Synonyms	Felodipine; (±)-Felodipine; Plendil (Trade Name); 4-(2,3-Dichlorophenyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid ethyl methyl ester; H 154/82; Ethyl methyl 4-(2,3-dichlorophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylate
EINECS	Contact for details

Quality Control

Our Felodipine is produced and tested to meet exacting pharmaceutical standards. Quality is assured through a comprehensive battery of analytical tests, including HPLC for purity and identity confirmation. We can supply material compliant with various pharmacopeial monographs, and a detailed Certificate of Analysis (COA) is provided with each batch to guarantee traceability and specification adherence.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (typically 15-25°C). Keep the container tightly sealed in a dry environment to maintain stability and prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.