Description

Quinapril CAS NO 85441-61-8 is a potent, competitive angiotensin-converting enzyme (ACE) inhibitor. This active pharmaceutical ingredient (API) is critical for the formulation of antihypertensive and heart failure medications, offering significant therapeutic value. It is primarily required by pharmaceutical manufacturers and research institutions engaged in cardiovascular drug development and production.

Application

• Primary Pharmaceutical Ingredient: Core API in the manufacture of oral tablets and capsules for treating hypertension (high blood pressure).
• Cardiac Therapy Formulations: Used in combination therapies for managing congestive heart failure and improving survival rates post-myocardial infarction.
• Generic Drug Production: Serves as the key component for generic versions of branded ACE inhibitor medications.
• Clinical Research: Employed in preclinical and clinical studies for investigating new cardiovascular disease treatments and delivery mechanisms.
• Reference Standard: Utilized as a high-purity analytical standard in quality control laboratories for method development and validation.
• Veterinary Medicine: Potential application in developing treatments for hypertension in companion animals.

Basic Information

Product Name	Quinapril
CAS No.	85441-61-8
Molecular Formula	C25H30N2O5
Molecular Weight	438.52 g/mol
Synonyms	Quinapril; Quinaprilum; Quinapril Hydrochloride (salt form); CI-906; Accupril (brand name); Acuitel; (3S)-2-[(2S)-2-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]propanoyl]-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; (S,S,S)-N-(1-Carboxy-3-phenylpropyl)-L-alanyl-L-proline ethyl ester
EINECS	Contact for details

Quality Control

Our Quinapril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identification, assay, and impurity profile analysis. A Certificate of Analysis (COA) detailing all test results against relevant specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Heavy Metals	≤ 20 ppm
Sulfated Ash	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.