Description

Dagapamil CAS NO 85247-76-3 is a high-purity pharmaceutical intermediate and research chemical belonging to the class of calcium channel blockers. This compound is of significant value for its role in the synthesis and development of advanced cardiovascular therapeutics. It is primarily required by pharmaceutical R&D laboratories, contract manufacturing organizations (CMOs), and academic institutions engaged in medicinal chemistry and pharmacology research.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel calcium channel blocker drugs and their analogs.
• Medicinal Chemistry Research: Used as a reference standard or starting material for structure-activity relationship (SAR) studies in cardiovascular drug discovery.
• Biochemical Research: Employed in in vitro studies to investigate calcium ion channel mechanisms and cellular signaling pathways.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical analysis (HPLC, LC-MS).
• Preclinical Development: Utilized in the formulation and testing stages of new drug candidates targeting hypertension and angina.

Basic Information

Product Name	Dagapamil
CAS No.	85247-76-3
Molecular Formula	C26H34N2O4
Molecular Weight	438.56 g/mol
Synonyms	Dagapamil; 2-[4-[(2S)-3,4-Dimethoxyphenethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)benzenepropanenitrile; (±)-Dagapamil; DAGAPAMIL; UNII-7D8K5785QY; 7D8K5785QY; Benzenepropanenitrile, 2-[4-[(2S)-3,4-dimethoxyphenethyl]methylamino]propyl]-3,4-dimethoxy-α-(1-methylethyl)-
EINECS	Contact for details

Quality Control

Our Dagapamil is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot undergoes comprehensive analytical testing, including HPLC for assay and related substances, residual solvent analysis, and identity confirmation (IR, MS). A Certificate of Analysis (COA) detailing all specifications and test results is provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to protect the product from moisture.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0%
Any single unknown impurity	≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C
Loss on Drying	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.