Description

Zabicipril CAS NO 83059-56-7 is a high-purity pharmaceutical intermediate and active ingredient. This compound is critical for the synthesis of advanced therapeutic agents, particularly in the cardiovascular and metabolic disease research sectors. It is primarily utilized by pharmaceutical manufacturers, biotechnology R&D laboratories, and fine chemical synthesis facilities requiring a reliable and consistent raw material for their production and development pipelines.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel Angiotensin-Converting Enzyme (ACE) inhibitors and related cardiovascular drugs.
• Active Pharmaceutical Ingredient (API) Development: Serves as a core structural component in the research and production of new therapeutic entities.
• Biochemical Research: Used in enzymatic and receptor-binding studies to investigate mechanisms of hypertension and heart failure.
• Preclinical & Clinical Trial Material: Supplied as a critical raw material for the manufacture of drug candidates under Good Manufacturing Practice (GMP) conditions for regulatory studies.
• Fine Chemical Synthesis: Employed in multi-step organic synthesis for creating complex, high-value molecular architectures.
• Reference Standard: Used as a certified reference material in analytical laboratories for quality control and method validation.

Basic Information

Product Name	Zabicipril
CAS No.	83059-56-7
Molecular Formula	C20H28N2O5S
Molecular Weight	408.51 g/mol
Synonyms	Zabicipril; (S)-1-[(S)-3-Mercapto-2-methylpropanoyl]pyrrolidine-2-carboxylic acid (4-phenylbutyl)amide; Cilazapril Impurity; Cilazapril Related Compound; ACE Inhibitor Intermediate; SQ 26,991; Zabiciprilum
EINECS	Contact for details

Quality Control

Our Zabicipril is manufactured under strict quality systems to ensure it meets the stringent requirements of pharmaceutical applications. Each batch undergoes comprehensive analytical testing, including identification, assay, and impurity profiling via HPLC, to confirm compliance with in-house specifications. A Certificate of Analysis (COA) detailing all test results is provided with every shipment. We support development with material suitable for research up to GMP-grade standards for clinical use.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.