Description

Perindopril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used primarily as an active pharmaceutical ingredient (API). Its high selectivity and efficacy make it a critical component in the formulation of cardiovascular medications for the treatment of hypertension and heart failure. This compound is essential for pharmaceutical manufacturers, research institutions, and contract development organizations engaged in producing and developing antihypertensive drugs.

Application

• Pharmaceutical API: Primary use as the active ingredient in prescription medications for managing high blood pressure (hypertension).
• Cardiovascular Drug Formulation: Key component in the production of tablets, capsules, and other dosage forms for chronic heart failure and stable coronary artery disease.
• Clinical Research: Used as a reference standard and raw material in pharmacokinetic, pharmacodynamic, and bioequivalence studies.
• Generic Drug Manufacturing: Serves as a critical starting material for companies producing generic versions of branded ACE inhibitor medications.
• Combination Therapies: Utilized in fixed-dose combination drugs, often paired with other antihypertensive agents like indapamide or amlodipine.

Basic Information

Product Name	Perindopril
CAS No.	82834-16-0
Molecular Formula	C19H32N2O5
Molecular Weight	368.47 g/mol
Synonyms	Perindopril; Perindoprilum; S-9490; Perindopril Erbumine; Coversyl; Aceon; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid; Perindopril Free Acid
EINECS	Contact for details

Quality Control

Our Perindopril is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use. We provide full traceability and Certificates of Analysis (COA) are available for all shipments, detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles to support our clients' regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a low-humidity environment to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time matches reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.