Description

Silabudipine is a high-purity pharmaceutical intermediate and research chemical. This compound is critical for the development and synthesis of advanced active pharmaceutical ingredients (APIs) targeting specific therapeutic pathways. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel calcium channel blocker candidates and related cardiovascular agents.
• Research & Development: Used as a reference standard and starting material in medicinal chemistry for structure-activity relationship (SAR) studies.
• Process Chemistry: Serves as a critical precursor in the scale-up and optimization of API manufacturing processes under GMP conditions.
• Academic Research: Employed in biochemical and pharmacological studies to investigate ion channel modulation and cellular signaling pathways.
• Fine Chemical Synthesis: A versatile intermediate for creating specialized derivatives and analogs for biological screening.

Basic Information

Product Name	Silabudipine
CAS No.	82587-26-6
Molecular Formula	C19H20N2O3
Molecular Weight	324.38 g/mol
Synonyms	Silabudipine; 2,6-Dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylic acid diethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, diethyl ester; Diethyl 2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-Dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylic acid diethyl ester; CAS 82587-26-6
EINECS	Contact for details

Quality Control

Our Silabudipine is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity. Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles. We adhere to relevant industry standards for pharmaceutical intermediates, and specifications can be tailored to meet specific project requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.