Description

Zofenopril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor, widely recognized for its cardiovascular applications. This active pharmaceutical ingredient (API) is critical for the development and manufacturing of antihypertensive and cardioprotective medications. It is primarily utilized by pharmaceutical companies and research institutions engaged in the production of finished dosage forms and advanced therapeutic studies. The compound is supplied with a commitment to high purity and reliable supply chain integrity for global pharmaceutical manufacturing.

Application

• Pharmaceutical API: Primary use as the active ingredient in the synthesis of antihypertensive drugs.
• Cardiovascular Research: A key compound in preclinical and clinical research for studying heart failure and post-myocardial infarction therapies.
• Generic Drug Manufacturing: Serves as the core component for producing generic versions of ACE inhibitor medications.
• Formulation Development: Used in R&D for developing various drug delivery systems, including tablets and capsules.
• Reference Standard: Employed as a high-purity analytical standard in quality control laboratories for HPLC and spectroscopic methods.

Basic Information

Product Name	Zofenopril
CAS No.	81872-10-8
Molecular Formula	C22H23NO5S2
Molecular Weight	445.56 g/mol
Synonyms	Zofenopril Calcium; SQ 26,991; (4S)-1-[(2S)-3-(Benzoylthio)-2-methylpropanoyl]-4-(phenylthio)-L-proline; Zopranol; Bifril; Zofenil; Zofenoprilum; Zofenopril Calcium Salt
EINECS	Contact for details

Quality Control

Our Zofenopril is manufactured under strict quality management systems, ensuring it meets the rigorous standards required for pharmaceutical applications. Each batch is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles. We adhere to relevant ICH guidelines and can supply material that aligns with pharmacopeial monographs for API manufacturing. Certificates of Analysis are available upon request to support your regulatory submissions.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed in a dry environment to prevent degradation. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5%
Single Maximum Impurity	≤0.5%
Loss on Drying	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.