Description

Rentiapril CAS NO 80830-42-8 is a high-purity pharmaceutical intermediate and active pharmaceutical ingredient (API). This compound is of significant importance in the synthesis of advanced therapeutic agents, particularly in the cardiovascular and metabolic disease research sectors. It is primarily needed by pharmaceutical manufacturers, R&D laboratories, and fine chemical synthesis facilities engaged in developing new drug candidates and generic formulations.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of angiotensin-converting enzyme (ACE) inhibitors and related cardiovascular drugs.
• Active Pharmaceutical Ingredient (API): Used in the formulation of finished dosage forms for clinical trials and commercial production.
• Biochemical Research: Serves as a reference standard and a tool compound in pharmacological studies targeting the renin-angiotensin system.
• Process Development: Utilized in scaling up and optimizing synthetic routes for cost-effective and compliant API manufacturing.
• Generic Drug Manufacturing: Essential for companies producing generic versions of established ACE inhibitor medications.
• Contract Research & Manufacturing (CRAM): Supplied to organizations offering custom synthesis and development services.

Basic Information

Product Name	Rentiapril
CAS No.	80830-42-8
Molecular Formula	C18H24N2O5S
Molecular Weight	380.46 g/mol
Synonyms	Rentiapril; Rentiaprilum; (2S,3aR,7aS)-1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]-octahydro-1H-indole-2-carboxylic acid; 1-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]propanoyl]-octahydroindole-2-carboxylic acid; SQ 27,519; SQ-27519; SQ27519
EINECS	Contact for details

Quality Control

Our Rentiapril is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical applications. We provide comprehensive Certificates of Analysis (COA) detailing purity, identity, and impurity profiles. Our quality commitment aligns with cGMP principles where applicable, ensuring reliable supply and consistent quality for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive); ensure the container is kept tightly sealed in a low-humidity environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.5%
Related Substances (HPLC)	Total impurities ≤1.5% Any single unknown impurity ≤0.5%
Water Content (KF)	≤0.5%
Residue on Ignition	≤0.1%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.