Description

Ramipril is a potent, long-acting angiotensin-converting enzyme (ACE) inhibitor used primarily as an active pharmaceutical ingredient (API). It is a critical compound for the development and manufacture of cardiovascular medications, specifically antihypertensive and heart failure drugs. This high-purity substance is essential for pharmaceutical manufacturers, research institutions, and contract development and manufacturing organizations (CDMOs) focused on cardiovascular therapies.

Application

• Pharmaceutical API: Primary use as the active ingredient in finished dosage forms for the treatment of hypertension (high blood pressure).
• Cardiovascular Drug Formulation: Manufacture of tablets, capsules, and other solid oral dosage forms containing Ramipril.
• Heart Failure Management: Used in medications aimed at improving survival and reducing hospitalization in patients with clinical heart failure.
• Post-Myocardial Infarction Therapy: Formulation of drugs to improve survival following a heart attack in clinically stable patients.
• Pharmaceutical Research & Development: Serves as a reference standard and key intermediate in the development of new cardiovascular drugs and generic formulations.
• Contract Manufacturing: Supplied to CDMOs for the production of branded and generic pharmaceutical products for global markets.

Basic Information

Product Name	Ramipril
CAS No.	8733-19-5
Molecular Formula	C23H32N2O5
Molecular Weight	416.51 g/mol
Synonyms	(2S,3aS,6aS)-1-[(2S)-2-[[(2S)-1-ethoxy-1-oxopentan-2-yl]amino]propanoyl]-3,3a,4,5,6,6a-hexahydro-2H-cyclopenta[b]pyrrole-2-carboxylic acid; Altace; Triatec; Ramace; Tritace; Cardace; Hypren; Ramipro; Unipril; Ramiprilum
EINECS	Contact for details

Quality Control

Our Ramipril CAS NO 8733-19-5 is manufactured under strict quality systems. Each batch undergoes comprehensive analytical testing to ensure it meets stringent specifications for identity, purity, and potency, aligning with major pharmacopeial standards such as USP and EP. A Certificate of Analysis (COA) documenting all test results is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment to maintain stability and potency.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to standard
Identification (HPLC)	Conforms to standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 2.0%
Specific Rotation	Contact for details

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.