Description

Mioflazine CAS NO 79467-24-6 is a selective calcium channel blocker and adenosine uptake inhibitor belonging to the chemical class of piperazine derivatives. This compound is of significant interest in pharmaceutical research and development for its potential cardioprotective and neuroprotective properties. It is primarily utilized by research institutions and pharmaceutical companies engaged in the discovery of novel therapeutic agents for cardiovascular and neurological disorders.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates targeting ion channel modulation.
• Cardiovascular Research: Investigated for its potential effects in models of ischemia-reperfusion injury, arrhythmias, and angina.
• Neurological Research: Studied for its role in adenosine-mediated pathways relevant to neuroprotection, epilepsy, and neurodegenerative conditions.
• Biochemical Tool Compound: Used in vitro and in vivo to study calcium homeostasis and purinergic signaling mechanisms.
• Reference Standard: Employed as an analytical standard in quality control laboratories for method development and validation.

Basic Information

Product Name	Mioflazine
CAS No.	79467-24-6
Molecular Formula	C22H26F3N3O2
Molecular Weight	421.46 g/mol
Synonyms	Mioflazine; R 51469; 1-[(4-(Trifluoromethyl)phenyl]methyl]-4-(2,3,4-trimethoxyphenyl)piperazine; R-51469; 1-[(4-(Trifluoromethyl)phenyl]methyl]-4-(2,3,4-trimethoxyphenyl)piperazine; 4-(2,3,4-Trimethoxyphenyl)-1-[[4-(trifluoromethyl)phenyl]methyl]piperazine
EINECS	Contact for details

Quality Control

Our Mioflazine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification by spectroscopic methods (IR, NMR, MS), purity assessment by HPLC, and control of related substances. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with your research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any individual impurity ≤ 0.5%; Total impurities ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.