Description

Emopamil is a potent calcium channel blocker belonging to the phenylalkylamine class, known for its high selectivity and research significance. This compound is primarily utilized in pharmaceutical research and development, particularly in the study of cardiovascular and neurological pathways. It is essential for researchers and manufacturers in the pharmaceutical and life science sectors seeking high-purity reference standards and active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Research & Development: Serves as a key reference standard and intermediate in the development of novel calcium channel modulators.
• Cardiovascular Studies: Used in preclinical research to investigate mechanisms related to vasodilation, hypertension, and cardiac muscle contractility.
• Neurological Research: Applied in studies focusing on cerebral vasospasm, neuroprotection, and the role of calcium influx in neuronal signaling.
• Active Pharmaceutical Ingredient (API): Employed as a high-purity building block in the synthesis of advanced pharmaceutical formulations.
• Biochemical Assays: Utilized as a selective tool compound in in vitro assays to study L-type calcium channels.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.

Basic Information

Product Name	Emopamil
CAS No.	78370-13-5
Molecular Formula	C24H32N2O3
Molecular Weight	396.53 g/mol
Synonyms	(±)-Emopamil; Emopamilum; LU-42668; LU 42668; 4-[(2-Isopropyl-5-methylcyclohexyl)oxy]-N,N-dimethyl-α-phenylbenzenepropanamine; 1-[4-[(1RS,2SR,5RS)-5-Isopropyl-2-methylcyclohexyloxy]phenyl]-3-phenyl-3-(dimethylamino)propan-1-one (common misassignment); 3-(Dimethylamino)-1-[4-[(1RS,2SR,5RS)-5-isopropyl-2-methylcyclohexyloxy]phenyl]-3-phenylpropan-1-one
EINECS	Contact for details

Quality Control

Our Emopamil is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting high standards for research and development use. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with every shipment and is available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept in a dry environment. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Single Unknown Impurity	≤ 0.5%
Loss on Drying	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.