Description

Isradipine is a high-purity dihydropyridine calcium channel blocker used primarily as a key pharmaceutical intermediate. This compound is critical for the research and development of cardiovascular therapeutics targeting hypertension and angina. It is essential for pharmaceutical manufacturers, R&D laboratories, and academic institutions engaged in cardiovascular drug synthesis and advanced pharmacological studies.

Application

• Pharmaceutical Intermediate: Primary use in the synthesis of finished dosage forms of Isradipine, an antihypertensive and antianginal medication.
• Active Pharmaceutical Ingredient (API) Research: Serves as a reference standard and building block in the development and analytical testing of calcium channel blocker APIs.
• Biochemical Research: Utilized in pharmacological studies to investigate calcium ion channel mechanisms and vascular smooth muscle function.
• Formulation Development: Employed in pre-formulation and formulation studies for creating tablets, capsules, and other drug delivery systems.
• Quality Control & Analytical Standards: Acts as a certified reference material (CRM) for HPLC, GC, and spectroscopic assays in pharmaceutical quality control laboratories.

Basic Information

Product Name	Isradipine
CAS No.	75695-93-1
Molecular Formula	C19H21N3O5
Molecular Weight	371.39 g/mol
Synonyms	PN 200-110; Isrodipine; Lomir; Prescal; DynaCirc; (4RS)-4-(4-Benzofurazanyl)-1,4-dihydro-2,6-dimethyl-3,5-pyridinedicarboxylic acid methyl 1-methylethyl ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(2-benzoxazolyl)-, methyl 1-methylethyl ester
EINECS	Contact for details

Quality Control

Our Isradipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling via HPLC, to ensure it meets high-grade pharmaceutical standards. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed to minimize exposure to atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	≥ 98.5%
Related Substances (HPLC)	Total impurities ≤ 1.0% Any single impurity ≤ 0.5%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.