Description

Bepridil Hydrochloride is a calcium channel blocker of the benzazepine class, primarily used in pharmaceutical research and development. Its significance lies in its unique pharmacological profile, offering a dual mechanism of action that blocks both L-type calcium channels and sodium channels. This compound is essential for researchers and manufacturers in the pharmaceutical industry focusing on cardiovascular therapeutics, particularly for investigating antianginal and antiarrhythmic agents. The product is supplied as a high-purity reference standard and active pharmaceutical ingredient (API) intermediate.

Application

• Pharmaceutical API Synthesis: A key intermediate in the manufacturing of the active pharmaceutical ingredient for cardiovascular medications.
• Reference Standard for QC: Used as a certified reference material in analytical laboratories for quality control and method validation.
• Pharmacological Research: Employed in preclinical and clinical studies to investigate mechanisms of calcium channel blockade and cardiac electrophysiology.
• Formulation Development: Serves as a model compound in the development of solid dosage forms, such as tablets and capsules.
• Biochemical Assays: Utilized in in-vitro assays to study ion channel function and screen for new therapeutic agents.

Basic Information

Product Name	Bepridil Hydrochloride
CAS No.	74764-40-2
Molecular Formula	C24H34N2O · HCl
Molecular Weight	403.00 g/mol
Synonyms	Bepridil HCl; 1-[3-(Isobutoxy)-2-(benzylmethylamino)propyl]pyrrolidine hydrochloride; Bepridil monohydrochloride; CERM 1978; (±)-Bepridil hydrochloride; Bepridil hydrochloride (USP); Angopril; Cordium; Vascor
EINECS	Contact for details

Quality Control

Our Bepridil Hydrochloride is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the requirements for pharmaceutical research and development. We provide full traceability and support current Good Manufacturing Practice (cGMP) principles for API intermediates. A detailed Certificate of Analysis (COA) is available for every lot, confirming compliance with in-house specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.