Description

Etanidazole CAS NO 74083-16-2 is a nitroimidazole-based radiosensitizer compound used in clinical and research oncology. Its primary value lies in its ability to selectively sensitize hypoxic tumor cells to the effects of radiation therapy, thereby enhancing treatment efficacy. This product is essential for pharmaceutical R&D laboratories, academic research institutions, and manufacturers developing advanced cancer therapeutics.

Application

• Radiation Therapy Adjuvant: Used as a hypoxic cell radiosensitizer in preclinical and clinical oncology research to improve the effectiveness of radiotherapy.
• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of more complex nitroimidazole derivatives for therapeutic applications.
• Biochemical Research: Employed in studies investigating tumor hypoxia, mechanisms of radiation sensitization, and cellular response to oxidative stress.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation in pharmaceutical manufacturing.
• Mechanistic Studies: Applied in research to understand the pharmacokinetics, metabolism, and biodistribution of radiosensitizing agents.

Basic Information

Product Name	Etanidazole
CAS No.	74083-16-2
Molecular Formula	C₇H₁₂N₄O₄
Molecular Weight	216.19 g/mol
Synonyms	Etanidazole; SR-2508; NSC 301467; 1-(2-Hydroxyethyl)-2-nitro-1H-imidazole; 2-Nitro-1-(2-hydroxyethyl)imidazole; NSC-301467; NSC301467; Radiosensitizer SR-2508
EINECS	Contact for details

Quality Control

Our Etanidazole is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, identity confirmation by IR and NMR spectroscopy, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with every shipment, ensuring traceability and compliance with research-grade specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain product integrity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.