Description

n-[4-[[(2-Amino-1,4-Dihydro-4-Oxopteridin-6-Yl)Methyl]Amino]Benzoyl]-L-Aspartic Acid is a high-purity, specialized biochemical intermediate of significant interest in advanced pharmaceutical research and development. This compound is valued for its role as a key building block in the synthesis of folate analogs and other complex molecules targeting critical biological pathways. It is primarily sought by R&D laboratories and manufacturers in the pharmaceutical and biotechnology sectors for the development of novel therapeutic agents and diagnostic tools.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of novel folate antagonists and related chemotherapeutic agents.
• Biochemical Research: Used as a substrate or inhibitor in enzymatic studies, particularly those involving folate-dependent enzymes.
• Antimetabolite Development: Serves as a core structure for developing compounds that interfere with DNA synthesis and cell proliferation.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method validation in pharmaceutical analysis.
• Precision Medicine: Investigated for use in targeted therapies and companion diagnostics.
• Academic Research: Utilized in university and institutional labs for fundamental studies in medicinal chemistry and cancer biology.

Basic Information

Product Name	n-[4-[[(2-Amino-1,4-Dihydro-4-Oxopteridin-6-Yl)Methyl]Amino]Benzoyl]-L-Aspartic Acid
CAS No.	14798-76-6
Molecular Formula	C19H19N7O6
Molecular Weight	441.40 g/mol
Synonyms	L-Aspartic Acid, N-[4-[[(2-amino-1,4-dihydro-4-oxo-6-pteridinyl)methyl]amino]benzoyl]-; 4-[[(2-Amino-4-oxo-1,4-dihydro-6-pteridinyl)methyl]amino]benzoic acid L-Aspartate; 6-[(p-Carboxybenzyl)amino]-2-amino-4-oxopteridine L-Aspartate; Pteroic acid aspartate derivative; Folate synthesis intermediate; PT523 Precursor; NSC 139490; CB 3717 Derivative
EINECS	Contact for details

Quality Control

Our n-[4-[[(2-Amino-1,4-Dihydro-4-Oxopteridin-6-Yl)Methyl]Amino]Benzoyl]-L-Aspartic Acid is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and stringent controls for residual solvents and impurities. Certificates of Analysis (COA) detailing all specifications are provided to ensure traceability and compliance with your research or cGMP-grade requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere for long-term stability. Keep the container tightly sealed in a dry environment to minimize exposure to moisture.

Specification

Item	Specification
Appearance	Yellow to light brown powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.