Description

Efaproxiral is a synthetic, small-molecule radiosensitizer designed to enhance the efficacy of radiation therapy. Its primary value lies in its ability to increase tumor oxygenation, thereby making hypoxic cancer cells more susceptible to radiation damage. This compound is of significant interest to pharmaceutical researchers and manufacturers developing advanced oncology therapeutics, particularly for solid tumors where hypoxia limits treatment success. Global suppliers require a reliable source of high-purity Efaproxiral CAS NO 131179-95-8 for preclinical development, clinical trials, and potential commercial-scale production.

Application

• Pharmaceutical Active Ingredient (API): Core component in the formulation of radiosensitizing drugs for cancer therapy.
• Oncology Research & Development: Critical reagent in preclinical and clinical studies investigating combination therapies with radiation.
• Mechanistic Studies: Used in biochemical research to study oxygen transport and tumor hypoxia modulation.
• Reference Standard: Serves as a high-purity analytical standard for quality control and method development in pharmaceutical labs.
• Drug Discovery: A key compound for structure-activity relationship (SAR) studies aimed at developing next-generation radiosensitizers.

Basic Information

Product Name	Efaproxiral
CAS No.	131179-95-8
Molecular Formula	C10H13NO3
Molecular Weight	195.22 g/mol
Synonyms	RSR13; 2-[4-[[(3,5-Dimethylanilino)carbonyl]methyl]phenoxy]-2-methylpropionic acid; Efaproxiral Sodium; RSR-13; BXCL-701 (component); NSC 726189; EINECS Not Assigned

Quality Control

Our Efaproxiral is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing to ensure identity, purity, and consistency, meeting the stringent requirements for pharmaceutical research and development. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting results for key parameters including assay, related substances, and residual solvents. We support compliance with cGMP and ICH Q7 guidelines for active pharmaceutical ingredients (APIs).

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The product is hygroscopic (moisture-sensitive) and should be handled under dry conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥98.0%
Related Substances (HPLC)	Total impurities ≤2.0% Any single impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Loss on Drying	≤1.0%
Heavy Metals	≤20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.