Description

Amifostine is a synthetic organic thiophosphate compound primarily recognized for its cytoprotective properties. This compound is of significant commercial and therapeutic interest due to its selective action in protecting healthy tissues from the damaging effects of radiation and certain chemotherapeutic agents. It is a critical raw material for the pharmaceutical industry, specifically in the development and manufacturing of radioprotectant and chemoprotectant drugs. Amifostine CAS NO 20537-88-6 is supplied under stringent quality control to meet the exacting standards of global pharmaceutical production.

Application

• Active Pharmaceutical Ingredient (API) in radioprotectant formulations.
• Key intermediate in the synthesis of chemoprotective drugs for oncology treatments.
• Research and development of novel cytoprotective agents in preclinical and clinical studies.
• Manufacturing of specialized injectable solutions for medical use.
• Reference standard in analytical laboratories for quality control and method validation.
• Component in studies exploring protection against nephrotoxicity caused by chemotherapeutic drugs like cisplatin.

Basic Information

Product Name	Amifostine
CAS No.	20537-88-6
Molecular Formula	C5H15N2O3PS
Molecular Weight	214.22 g/mol
Synonyms	Ethiofos; WR-2721; Gammaphos; S-2-(3-Aminopropylamino)ethylphosphorothioate; S-2-(3-Aminopropylamino)ethyl dihydrogen phosphorothioate; Amifostine Trihydrate; NSC-296961; YM-08310
EINECS	Contact for details

Quality Control

Our Amifostine is manufactured under a quality management system designed for pharmaceutical ingredients. Each batch undergoes comprehensive analytical testing, including identification, purity assay, and impurity profiling, to ensure it meets stringent specifications. A Certificate of Analysis (COA) detailing the results for all critical parameters is provided with every shipment to guarantee traceability and compliance with relevant guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which can affect stability and purity.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference standard
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Individual impurity ≤ 0.5%; Total impurities ≤ 1.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.