Description

(6R,S)-5-Formyl-5,6,7,8-Tetrahydrofolsaeure is a key folate derivative and an important intermediate in biochemical pathways. This compound matters for its role in one-carbon metabolism, serving as a critical building block for the synthesis of more complex folate coenzymes. It is primarily needed by pharmaceutical manufacturers and research institutions developing novel therapeutics, diagnostic agents, and advanced nutritional supplements.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of active pharmaceutical ingredients (APIs) for oncology and metabolic disorder treatments.
• Biochemical Research: Used as a standard or reagent in enzymatic studies and metabolic pathway analysis related to folate cycles.
• Nutraceutical Development: Serves as a starting material for the production of advanced, high-bioavailability folate forms in dietary supplements.
• Diagnostic Reagent Manufacturing: Employed in the formulation of assay kits and diagnostic tests that measure folate levels or related enzymatic activity.
• Cell Culture Media Supplement: Used in specialized cell culture formulations to support the growth of demanding cell lines in bioprocessing.

Basic Information

Product Name	(6R,S)-5-Formyl-5,6,7,8-Tetrahydrofolsaeure
CAS No.	73951-54-9
Molecular Formula	C20H23N7O7
Molecular Weight	473.44 g/mol
Synonyms	5-Formyl-5,6,7,8-tetrahydrofolic acid; 5-CHO-THF; Folinic acid intermediate; 5-Formyltetrahydrofolate; (6R,S)-5-Formyltetrahydrofolic acid; Leucovorin impurity; (6RS)-5-Formyl-5,6,7,8-tetrahydrofolate; 5-Formyl-THF
EINECS	Contact for details

Quality Control

Our (6R,S)-5-Formyl-5,6,7,8-Tetrahydrofolsaeure is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for pharmaceutical and research applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under dry, inert conditions to maintain stability and purity.

Specification

Item	Specification
Appearance	Yellow to orange powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 2.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.