Description

1,4-Dihydro-2,6-Dimethyl-4-(4-Methylphenyl)-3,5-Pyridinedicarboxylic Acid Dimethyl Ester is a high-purity dihydropyridine derivative, a key structural motif in medicinal chemistry. This compound is valued for its role as a critical pharmaceutical intermediate and a versatile building block in advanced organic synthesis. It is primarily required by R&D laboratories and manufacturers in the pharmaceutical and fine chemical industries for developing active pharmaceutical ingredients (APIs) and novel chemical entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of calcium channel blockers and other dihydropyridine-based active pharmaceutical ingredients (APIs).
• Organic Synthesis Building Block: Used in research and development for constructing complex heterocyclic compounds and novel molecular scaffolds.
• Chemical Research (R&D): Serves as a reference standard and a starting material in academic and industrial research for studying structure-activity relationships.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals requiring high-purity, functionalized dihydropyridine cores.

Basic Information

Product Name	1,4-Dihydro-2,6-Dimethyl-4-(4-Methylphenyl)-3,5-Pyridinedicarboxylic Acid Dimethyl Ester
CAS No.	73257-48-4
Molecular Formula	C18H21NO4
Molecular Weight	315.36 g/mol
Synonyms	Dimethyl 2,6-Dimethyl-4-(4-methylphenyl)-1,4-dihydropyridine-3,5-dicarboxylate; 4-(p-Tolyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid Dimethyl Ester; 4-(4-Methylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid Dimethyl Ester; DHP Derivative; Dihydropyridine Ester; Hantzsch Ester Derivative; 1,4-DHP Intermediate
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-2,6-Dimethyl-4-(4-Methylphenyl)-3,5-Pyridinedicarboxylic Acid Dimethyl Ester is produced under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) are provided with each shipment, detailing all relevant specifications. We can support development and commercial projects requiring compliance with cGMP and other regulatory standards.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive); keep the container tightly sealed in a dry environment to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.