Description

Riodipine is a high-purity pharmaceutical intermediate and research chemical. This compound is of significant interest in the development and synthesis of calcium channel blockers for cardiovascular research. It is primarily utilized by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic institutions engaged in medicinal chemistry and pharmacology studies.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of advanced dihydropyridine-based calcium channel antagonists.
• Medicinal Chemistry Research: Used as a reference standard or precursor in structure-activity relationship (SAR) studies for cardiovascular drug discovery.
• Active Pharmaceutical Ingredient (API) Development: Serves as a critical starting material or intermediate in the process development and scale-up of novel therapeutic agents.
• Biochemical Research: Employed in in-vitro studies to investigate calcium channel modulation and related cellular pathways.
• Fine Chemical Synthesis: Utilized in custom synthesis and contract manufacturing for specialized chemical entities.

Basic Information

Product Name	Riodipine
CAS No.	71653-63-9
Molecular Formula	C19H20N2O6
Molecular Weight	372.37 g/mol
Synonyms	Riodipine; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-, methyl 1-methylethyl ester; Isopropyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-3,5-pyridinedicarboxylate; 4-(3-Nitrophenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid isopropyl methyl ester; CAS 71653-63-9
EINECS	Contact for details

Quality Control

Our Riodipine is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements for pharmaceutical research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Keep the container tightly sealed in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Yellow to light brown crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.