Description

1,4-Dihydro-2,6-Dimethyl-4-Phenyl-3,5-Pyridinecarboxylic Acid Dimethyl Ester is a high-purity dihydropyridine derivative, a critical intermediate in the synthesis of advanced pharmaceutical compounds. Its value lies in its role as a key building block for calcium channel blockers and other active pharmaceutical ingredients (APIs), ensuring reliable and scalable production for drug manufacturers. This product is essential for R&D laboratories, fine chemical synthesis, and commercial API production within the global pharmaceutical and life sciences industries.

Application

• Pharmaceutical Intermediate: A crucial precursor in the synthesis of Nifedipine, a widely used calcium channel blocker for treating hypertension and angina.
• API Synthesis: Serves as a core building block for other 1,4-dihydropyridine-class active pharmaceutical ingredients (APIs).
• Research & Development: Used in medicinal chemistry for developing new cardiovascular and neurological drug candidates.
• Fine Chemical Production: Employed in custom synthesis and contract manufacturing of complex organic molecules.
• Chemical Reference Standard: Provides a high-purity standard for analytical method development and quality control in pharmaceutical labs.

Basic Information

Product Name	1,4-Dihydro-2,6-Dimethyl-4-Phenyl-3,5-Pyridinecarboxylic Acid Dimethyl Ester
CAS No.	70677-78-0
Molecular Formula	C17H19NO4
Molecular Weight	301.34 g/mol
Synonyms	Dimethyl 2,6-Dimethyl-4-phenyl-1,4-dihydropyridine-3,5-dicarboxylate; 1,4-DHP Derivative; Nifedipine Intermediate; Hantzsch Ester Derivative; DHP Ester; 3,5-Pyridinedicarboxylic acid, 1,4-dihydro-2,6-dimethyl-4-phenyl-, dimethyl ester; 4-Phenyl-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic acid dimethyl ester
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-2,6-Dimethyl-4-Phenyl-3,5-Pyridinecarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure high purity and consistency suitable for pharmaceutical applications. Certificates of Analysis (COA) detailing all specifications are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (15-25°C). This compound is strictly light-sensitive and must be protected from all light exposure during storage and handling to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.