Description

Perindopril L-Arginine is a high-purity, non-hygroscopic salt form of the widely prescribed ACE inhibitor, perindopril. This specific salt form offers enhanced stability and is a critical active pharmaceutical ingredient (API) for the formulation of cardiovascular medications. It is essential for pharmaceutical manufacturers and research institutions developing treatments for hypertension and heart failure. The compound is supplied to meet the stringent requirements of global pharmacopoeial standards.

Application

• Primary Pharmaceutical API: Core active ingredient in the manufacture of antihypertensive and heart failure medications.
• Finished Dosage Form Development: Used in the R&D and production of tablets, capsules, and other solid oral dosage forms.
• Generic Drug Manufacturing: A key component for companies producing bioequivalent generic versions of branded perindopril-based drugs.
• Clinical Research Materials: Serves as a reference standard or raw material in preclinical and clinical trial studies.
• Pharmaceutical Intermediates: May be utilized in further synthetic steps for novel drug development programs.

Basic Information

Product Name	Perindopril L-Arginine
CAS No.	612548-45-5
Molecular Formula	C23H44N6O7
Molecular Weight	516.64 g/mol
Synonyms	Perindopril Arginine; Perindopril L-Arginine Salt; (2S,3aS,7aS)-1-[(2S)-2-[[(1S)-1-(Ethoxycarbonyl)butyl]amino]propanoyl]-2,3,3a,4,5,6,7,7a-octahydroindole-2-carboxylic acid – (2S)-2-amino-5-guanidinopentanoic acid (1:1); S-9780; Coversyl Arginine; Aceon (arginine salt form); Perindoprilat Arginine Ester; Perindopril Arginine Dihydrate (common form)
EINECS	Contact for details

Quality Control

Our Perindopril L-Arginine is manufactured under strict quality management systems. Each batch is tested to ensure compliance with major pharmacopoeial standards such as USP, EP, and BP. A comprehensive Certificate of Analysis (COA) is provided with every shipment, detailing results for identity, purity, assay, and specified impurities. We are committed to supply chain reliability and consistent quality to support your regulatory filings and production schedules.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). Although this salt form is noted for its stability, it is advisable to minimize exposure to excessive humidity. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White or almost white crystalline powder
Identification (IR)	Conforms to reference standard
Identification (HPLC)	Retention time corresponds to reference
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Related Substances (HPLC)	Individual impurity: ≤ 0.5% Total impurities: ≤ 1.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Specific Rotation	Contact for details
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.