Description

Bepridil is a calcium channel blocker belonging to the class of benzylamine derivatives, identified by CAS NO 64706-54-3. This compound is of significant interest in pharmaceutical research and development due to its specific mechanism of action on cardiac and vascular smooth muscle cells. It serves as a critical intermediate and reference standard for researchers and manufacturers in the life sciences sector. Key industries that utilize this material include pharmaceutical R&D, contract manufacturing organizations (CMOs), and academic research institutions.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of active pharmaceutical ingredients (APIs) for cardiovascular research.
• Reference Standard: Used in analytical laboratories for method development, validation, and quality control testing via HPLC, LC-MS, or NMR.
• Biochemical Research: Employed in vitro and ex vivo studies to investigate calcium channel physiology, vasodilation, and anti-anginal mechanisms.
• Preclinical Development: Utilized in the formulation of dosage forms for pharmacokinetic and pharmacodynamic studies in animal models.
• Contract Manufacturing: Supplied to CMOs and CDMOs for scale-up synthesis under cGMP conditions for clinical trial material production.

Basic Information

Product Name	Bepridil
CAS No.	64706-54-3
Molecular Formula	C24H34N2O
Molecular Weight	366.54 g/mol
Synonyms	Bepridil Hydrochloride (Monohydrochloride); 1-[3-(Isobutoxy)-2-[(benzylmethylamino)methyl]propyl]pyrrolidine; Bepridilum; CERM-1978; Cordium; Angopril; Vascor; Bepricol; UNII-6W6P6SFS8I; β-[(2-Methylpropoxy)methyl]-N-phenyl-N-(phenylmethyl)-1-pyrrolidineethanamine
EINECS	Contact for details

Quality Control

Our Bepridil is manufactured and tested to meet high-purity standards suitable for research and development. Each batch undergoes rigorous analytical testing, including identification, assay, and impurity profiling, to ensure consistency and reliability. Certificates of Analysis (COA) detailing specific results for purity (typically ≥98% by HPLC), residual solvents, and related substances are available upon request. We support compliance with relevant regulatory frameworks for pharmaceutical intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed to prevent absorption of atmospheric moisture. For long-term storage, consider using desiccants.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Loss on Drying	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.