Description

1,4-Dihydro-2,6-Dimethyl-4-[o-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester is a high-purity, synthetic organic compound belonging to the dihydropyridine class, valued for its role as a key pharmaceutical intermediate. Its molecular structure, featuring a trifluoromethylphenyl group, makes it a critical building block in the synthesis of advanced active pharmaceutical ingredients (APIs). This compound is essential for research and development laboratories and production facilities in the global pharmaceutical and fine chemical industries.

Application

• Pharmaceutical Intermediate: Serves as a crucial precursor in the synthesis of calcium channel blockers and other cardiovascular drugs.
• Chemical Research & Development: Used as a building block for novel drug candidates and in structure-activity relationship (SAR) studies.
• Fine Chemical Synthesis: Employed in the multi-step synthesis of complex organic molecules for medicinal chemistry.
• Reference Standard: Utilized as an analytical standard in quality control laboratories for method development and validation.
• Academic Research: Applied in university and institutional research exploring dihydropyridine chemistry and its biological activities.

Basic Information

Product Name	1,4-Dihydro-2,6-Dimethyl-4-[o-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester
CAS No.	53219-40-2
Molecular Formula	C18H18F3NO4
Molecular Weight	369.34 g/mol
Synonyms	Dimethyl 1,4-Dihydro-2,6-dimethyl-4-(2-(trifluoromethyl)phenyl)-3,5-pyridinedicarboxylate; 2,6-Dimethyl-4-(2-trifluoromethylphenyl)-1,4-dihydropyridine-3,5-dicarboxylic Acid Dimethyl Ester; 4-(o-Trifluoromethylphenyl)-2,6-dimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid Dimethyl Ester; Felodipine Impurity; Felodipine Related Compound A; o-Trifluoromethyl Derivative of Nifedipine
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-2,6-Dimethyl-4-[o-(Trifluoromethyl)Phenyl]-3,5-Pyridinedicarboxylic Acid Dimethyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and IR spectroscopy, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided with every shipment to support your quality assurance and regulatory compliance needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0%
Any single impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH guidelines
Loss on Drying	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.