Description

(2R-(2Alpha,4Beta,5Alpha))-5-Methyl-1-(Tetrahydro-4-Hydroxy-5-(1H-Tetr Azol-5-Yl)-2-Furanyl)-2,4(1H,3H)-Pyrimidinedione is a high-purity, structurally complex heterocyclic compound featuring a fused pyrimidinedione and tetrazole ring system. This compound is of significant interest in advanced pharmaceutical research and development, particularly as a key synthetic intermediate or a potential active pharmaceutical ingredient (API) precursor. It is primarily sought by pharmaceutical R&D laboratories, fine chemical manufacturers, and academic research institutions engaged in the synthesis of novel therapeutic agents.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of nucleoside analog drugs and other complex bioactive molecules.
• Antiviral Drug Research: Investigated for its potential as a precursor in the development of antiviral agents, given its structural similarity to modified nucleosides.
• Enzyme Inhibition Studies: Used in biochemical research to study inhibition of specific enzymes like reverse transcriptase or polymerases.
• Medicinal Chemistry: A valuable scaffold for structure-activity relationship (SAR) studies and the design of new chemical entities in drug discovery programs.
• Reference Standard: Employed as a high-purity analytical standard for quality control and method development in pharmaceutical analysis.
• Chemical Biology Probes: Utilized in the development of molecular probes to study biological pathways and target engagement.

Basic Information

Product Name	(2R-(2Alpha,4Beta,5Alpha))-5-Methyl-1-(Tetrahydro-4-Hydroxy-5-(1H-Tetr Azol-5-Yl)-2-Furanyl)-2,4(1H,3H)-Pyrimidinedione
CAS No.	52995-50-3
Molecular Formula	C10H12N6O4
Molecular Weight	280.24 g/mol
Synonyms	5-Methyl-1-(tetrahydro-4-hydroxy-5-(1H-tetrazol-5-yl)-2-furanyl)-2,4(1H,3H)-pyrimidinedione; (2R,4S,5R)-5-Methyl-1-(tetrahydro-4-hydroxy-5-(1H-tetrazol-5-yl)-2-furanyl)pyrimidine-2,4(1H,3H)-dione; 5-Methyl-1-[(2R,4S,5R)-4-hydroxy-5-(1H-tetrazol-5-yl)oxolan-2-yl]pyrimidine-2,4-dione; A potential nucleoside analog intermediate.
EINECS	Contact for details

Quality Control

Our (2R-(2Alpha,4Beta,5Alpha))-5-Methyl-1-(Tetrahydro-4-Hydroxy-5-(1H-Tetr Azol-5-Yl)-2-Furanyl)-2,4(1H,3H)-Pyrimidinedione is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and IR for structural confirmation, and residual solvent analysis. A detailed Certificate of Analysis (COA) is provided with each shipment, ensuring traceability and compliance with your research or production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); therefore, the container should be kept tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines
Heavy Metals	< 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.