Description

Ilepatril is a high-purity, non-peptide vasopeptidase inhibitor compound of significant interest in pharmaceutical research and development. This molecule is a key intermediate or active pharmaceutical ingredient (API) for investigating novel therapeutic pathways, particularly in cardiovascular and renal disease research. It is essential for pharmaceutical manufacturers, contract research organizations (CROs), and academic institutions engaged in the synthesis of advanced drug candidates. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: Primary use as a building block in the synthesis of advanced vasopeptidase inhibitor drug candidates.
• Cardiovascular Research: Critical material for preclinical and clinical studies targeting hypertension and heart failure mechanisms.
• Renal Disease Studies: Used in research exploring therapeutic options for chronic kidney disease and related conditions.
• API Development: Serves as an Active Pharmaceutical Ingredient (API) or a key precursor in the development of finished dosage forms.
• Biochemical Assay Standard: Employed as a reference standard in analytical method development and validation for pharmacokinetic studies.
• Process Chemistry: Utilized in route scouting, optimization, and scale-up activities within process R&D departments.

Basic Information

Product Name	Ilepatril
CAS No.	473289-62-2
Molecular Formula	C23H32N2O5S
Molecular Weight	448.58 g/mol
Synonyms	(2S,4S)-4-[(2S)-2-[[(1S)-1-Carboxy-3-phenylpropyl]amino]-1-oxopropyl]-1-methyl-2-thiomorpholinecarboxylic acid 1-oxide; Ilepatrilum; S 21402; Fasidotril; Vasopeptidase Inhibitor S21402; (4S)-1-Methyl-4-[(2S)-2-[[(1S)-3-phenyl-1-(carboxymethyl)propyl]amino]propanoyl]-2-sulfanylidene-1,4-thiazinane-3-carboxylic acid
EINECS	Contact for details

Quality Control

Our Ilepatril is manufactured under strict quality management systems to ensure it meets the exacting standards required for pharmaceutical research. Each batch undergoes comprehensive analytical testing, including identity confirmation, purity assay, and impurity profiling via advanced techniques like HPLC and LC-MS. A Certificate of Analysis (COA) is provided with every shipment, detailing all critical quality attributes. We support compliance with cGMP and ICH guidelines for API development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation. Ensure the storage area is well-ventilated and away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.