Description

1,4-Dihydro-1,2,6-Trimethyl-4-Phenyl-3,5-Pyridinedicarboxylic Acid Diethyl Ester is a high-purity dihydropyridine derivative, a key structural motif in medicinal chemistry. This compound matters as a versatile pharmaceutical intermediate and a valuable building block for research into calcium channel modulators. It is primarily needed by manufacturers and R&D teams in the pharmaceutical, agrochemical, and fine chemical synthesis sectors for developing new active ingredients.

Application

• Pharmaceutical Intermediate: Critical precursor in the synthesis of dihydropyridine-class calcium channel blockers and other bioactive molecules.
• Research & Development: Serves as a key scaffold in medicinal chemistry for drug discovery programs targeting cardiovascular and neurological disorders.
• Agrochemical Synthesis: Used in the development of novel pesticides and herbicides, leveraging its heterocyclic core structure.
• Fine Chemical Production: Acts as a building block for synthesizing complex organic compounds, dyes, and functional materials.
• Academic Research: Utilized in universities and research institutes for studying chemical reactions, mechanisms, and structure-activity relationships.
• Chemical Reference Standard: Supplied as a high-purity standard for analytical method development and quality control in API manufacturing.

Basic Information

Product Name	1,4-Dihydro-1,2,6-Trimethyl-4-Phenyl-3,5-Pyridinedicarboxylic Acid Diethyl Ester
CAS No.	3274-34-8
Molecular Formula	C21H25NO4
Molecular Weight	355.43 g/mol
Synonyms	Diethyl 1,4-Dihydro-1,2,6-trimethyl-4-phenyl-3,5-pyridinedicarboxylate; 3,5-Pyridinedicarboxylic Acid, 1,4-Dihydro-1,2,6-trimethyl-4-phenyl-, Diethyl Ester; 4-Phenyl-1,2,6-trimethyl-1,4-dihydropyridine-3,5-dicarboxylic Acid Diethyl Ester; 1,4-DHP Derivative; DHP Ester; NSC 163049; Ethyl Ester of Hantzsch Ester Analog
EINECS	Contact for details

Quality Control

Our 1,4-Dihydro-1,2,6-Trimethyl-4-Phenyl-3,5-Pyridinedicarboxylic Acid Diethyl Ester is manufactured under a strict quality management system. Every batch undergoes rigorous analytical testing, including HPLC, GC, and NMR, to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with each shipment to support your quality assurance protocols.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its light-sensitive and easily oxidized nature, it is recommended to store the product under an inert atmosphere (e.g., nitrogen or argon) for long-term stability. Keep away from heat, sparks, and open flame.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Related Substances (HPLC)	Total impurities ≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.