Description

Benazepril Hydrochloride is a high-purity active pharmaceutical ingredient (API) primarily used as an angiotensin-converting enzyme (ACE) inhibitor. This compound is critical for the formulation of antihypertensive and heart failure medications, offering reliable therapeutic efficacy. It is essential for pharmaceutical manufacturers and R&D laboratories engaged in cardiovascular drug development and generic drug production.

Application

• Pharmaceutical API: Primary active ingredient in prescription medications for treating hypertension (high blood pressure).
• Cardiovascular Formulations: Used in the development and production of drugs for heart failure management.
• Generic Drug Manufacturing: Key component for producing bioequivalent generic versions of brand-name ACE inhibitors.
• Research & Development: Serves as a reference standard and building block in pharmacological and clinical research studies.
• Veterinary Medicine: Potential application in developing cardiovascular treatments for animals.

Basic Information

Product Name	Benazepril Hydrochloride
CAS No.	3202-55-9
Molecular Formula	C24H28N2O5•HCl
Molecular Weight	460.95 g/mol
Synonyms	Benazepril HCl; Benazepril Hydrochloride; CGS-14824A; CGS 14824; (3S)-3-[[(1S)-1-Ethoxycarbonyl-3-phenylpropyl]amino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepine-1-acetic acid hydrochloride; Benzazepril Hydrochloride; Lotensin (brand name API)
EINECS	Contact for details

Quality Control

Our Benazepril Hydrochloride is manufactured under strict quality management systems. The product undergoes rigorous analytical testing to ensure it meets high-purity standards suitable for pharmaceutical use, including identification, assay, and impurity profile checks. A comprehensive Certificate of Analysis (COA) is provided with each batch, detailing specifications and test results. We can support compliance with relevant pharmacopoeial standards (e.g., USP, EP) upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time corresponds to reference standard
Assay (HPLC)	98.0% - 102.0% (on anhydrous basis)
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm
Related Substances (HPLC)	Total impurities ≤ 1.0%; Individual unspecified impurity ≤ 0.2%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.