Description

Amlodipine n-Lactoside is a novel, high-purity chemical intermediate designed for advanced pharmaceutical research and development. This compound is critical for the synthesis of next-generation calcium channel blockers and related therapeutic agents, offering researchers a reliable building block with defined stereochemistry. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on cardiovascular and metabolic disease drug discovery.

Application

• Pharmaceutical Intermediate: Serves as a key precursor in the synthesis of novel amlodipine analogs and prodrugs for enhanced bioavailability.
• Research & Development: Used in medicinal chemistry programs for structure-activity relationship (SAR) studies and lead optimization.
• Process Chemistry: Employed in route scouting and scale-up development for new active pharmaceutical ingredients (APIs).
• Reference Standard: Acts as a certified reference material (CRM) for analytical method development and quality control in API manufacturing.
• Academic Research: Utilized in university and institutional labs studying calcium channel modulation and glycosylated drug conjugates.

Basic Information

Product Name	Amlodipine n-Lactoside
CAS No.	2173291-00-2
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Amlodipine lactoside; Amlodipine glycoside conjugate; 3-Ethyl 5-methyl (4RS)-2-[(2-aminoethoxy)methyl]-4-(2-chlorophenyl)-6-methyl-1,4-dihydro-3,5-pyridinedicarboxylate lactoside; 1,4-Dihydro-2,6-dimethyl-4-(2-chlorophenyl)-3,5-pyridinedicarboxylic acid 3-ethyl 5-methyl ester lactoside derivative; Norvasc lactoside derivative; AML lactoside; (4R,S)-Amlodipine n-Lactoside
EINECS	Contact for details

Quality Control

Our Amlodipine n-Lactoside is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, chiral analysis, and structural confirmation via NMR and MS, to ensure it meets the stringent requirements for pharmaceutical research. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability and consistent quality for your critical projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and should be handled under anhydrous conditions when necessary.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.