Description

3-Acetoxy-5-[2-(Dimethylamino)Ethyl]-2,3-Dihydro-2-(4-Methoxyphenyl)-1,5-Benzothiazepin-4(5H)-One Monohydrochloride is a high-purity, complex organic compound primarily utilized as a key pharmaceutical intermediate. Its value lies in its specific benzothiazepine core structure, which is of significant interest in medicinal chemistry research and development. This product is essential for researchers and manufacturers in the pharmaceutical industry, particularly those focused on developing novel therapeutic agents targeting cardiovascular and central nervous system disorders.

Application

• Pharmaceutical Intermediate: Serves as a critical building block in the synthesis of novel benzothiazepine-based active pharmaceutical ingredients (APIs).
• Medicinal Chemistry Research: Used in drug discovery programs for structure-activity relationship (SAR) studies and lead optimization.
• Reference Standard: Employed as an analytical standard for quality control and method development in pharmaceutical analysis.
• Preclinical Development: Utilized in the production of compounds for pharmacological and toxicological evaluation.
• Chemical Synthesis: Acts as a versatile precursor for further chemical modifications to create derivative libraries.

Basic Information

Product Name	3-Acetoxy-5-[2-(Dimethylamino)Ethyl]-2,3-Dihydro-2-(4-Methoxyphenyl)-1,5-Benzothiazepin-4(5H)-One Monohydrochloride
CAS No.	23515-59-5
Molecular Formula	C24H29N2O4S • HCl
Molecular Weight	477.02 g/mol
Synonyms	Diltiazem Impurity; Diltiazem Related Compound; 3-Acetyl Diltiazem Hydrochloride; 3-Acetoxy Diltiazem Hydrochloride; 2,3-Dihydro-3-acetoxy-2-(4-methoxyphenyl)-5-[2-(dimethylamino)ethyl]-4H-1,5-benzothiazepin-4-one Hydrochloride; 3-O-Acetyl Diltiazem Hydrochloride; (2S,3S)-3-Acetoxy-5-[2-(dimethylamino)ethyl]-2,3-dihydro-2-(4-methoxyphenyl)-1,5-benzothiazepin-4(5H)-one Hydrochloride
EINECS	Contact for details

Quality Control

Our 3-Acetoxy-5-[2-(Dimethylamino)Ethyl]-2,3-Dihydro-2-(4-Methoxyphenyl)-1,5-Benzothiazepin-4(5H)-One Monohydrochloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided for every shipment to guarantee traceability and batch-to-batch consistency.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed in a dry environment to prevent moisture absorption, which may affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to reference spectrum
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥ 98.0%
Related Substances (HPLC)	Total impurities ≤ 2.0% Any single impurity ≤ 1.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.